Use of mupirocin ointment in these age groups is supported by evidence from adequate and well-controlled studies of mupirocin ointment in impetigo in pediatric patients studied as a part of the pivotal clinical trials. Mupirocin exhibits in vitro MICs of 1 mcg/mL or less against most (>90%) strains of methicillin-susceptible S. aureus; however, the safety and effectiveness of mupirocin calcium in eradicating nasal colonization of and preventing subsequent infections due to methicillin-susceptible S. aureus have not been established. Chemically, it is (αE,2S,3R,4R,5S)-5-[(2S,3S,4S,5S)-2,3-epoxy-5-hydroxy-4-methylhexyl]tetrahydro-3,4-dihydroxy-β-methyl-2H-pyran-2-crotonic acid, ester with 9-hydroxynonanoic … BACTROBAN nasal ointment is a white to off-white ointment that contains 20 mg (2% w/w) of mupirocin in a soft white ointment base supplied in single-use 1‑gram tubes. COST-EFFECTIVENESS ANALYSIS OF NASAL MUPIROCIN 153 FIGURE 1.
Two full economic analyses 50, 51 were identified.. A cost-effectiveness analysis conducted in the Netherlands 50 compared mupirocin calcium ointment treatment with no preventative treatment in cardiothoracic surgery patients. Carriers were prescribed mupirocin nasal ointment, chlorhexidine shower and mouthwash. 4 CONTRAINDICATIONS BACTROBAN nasal ointment is contraindicated in patients with known hypersensitivity to mupirocin or any of the excipients of BACTROBAN nasal ointment. Journal of Hospital Infection (1991) 19 (Supplement B), 41^6 The use of nasal mupirocin ointment to prevent Staphylococcus aureus bacteraemias in haemodialysis patients: an analysis of cost-effectiveness J. R. Boelaert, Y. E.1. BACTROBAN Nasal is a white to off-white ointment that contains 2.15% w/w mupirocin calcium (equivalent to 2.0% pure mupirocin free acid) in a soft white ointment base. Effectiveness of decolonization was evaluated with a postoperative nasal sample. It comes as a topical ointment, topical cream, and nasal ointment. Simpl e decision model for patients undergoing total joint arthroplasty (TJA) to have no treatment, be treated preoperatively with mupirocin, or be screened and then Staphylococcus, if aureus carriage is detected, treated with mupirocin. Find user ratings and reviews for Bactroban Nasal nasal on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction
A. The use of nasal mupirocin ointment to prevent Staphylococcus aureus bacteraemias in haemodialysis patients: an analysis of cost-effectiveness. SSI, surgical site infection. 4 CONTRAINDICATIONS BACTROBAN nasal ointment is contraindicated in patients with known hypersensitivity to mupirocin or any of the excipients of BACTROBAN nasal ointment. J Hosp Infect 1991 ;19: Suppl B : 41 - 46 Crossref This analysis was based on a study of 1796 patients using a historical control. After application, the nostrils should be closed by pressing together and releasing the sides of the nose repetitively for approximately 1 minute. BACTROBAN (mupirocin calcium) nasal ointment, 2% contains the dihydrate crystalline calcium hemi-salt of the antibacterial drug, mupirocin. Effectiveness of decolonization was evaluated with a postoperative nasal sample. Bactroban Nasal Ointment - Clinical Pharmacology Pharmacokinetics (See INDICATIONS AND USAGE.) 1,2,3,4,5 After application of mupirocin for 5 days, there is approximately 97% eradication of nasal carriage of S. aureus 6 and, in comparison with historical controls, a reduction in the risk of ESI and peritonitis caused by S. aureus. S. aureus decolonization with nasal mupirocin for patients undergoing TJA should be considered. Compliance was evaluated objectively by determination of nasal mupirocin concentration using UPLC-MS/MS and self-reported by questionnaire.